Is it possible? Probably not until recently. Many large companies have been investigating migrating to other programming languages to boost their operation performance and save on server prices but there is no need really. Python can be right tool for the job and there is a lot of work around performance in the community happening. CPython 3.6 boosted overall interpreter performance with new dictionary implementation, CPython 3.7 is gonna be even faster thanks to introducing faster call convention and dictionary lookup caches. For number crunching tasks you can use PyPy with its just-in-time code compilation. Since recently it can run NumPy test suite and improved overall compatibility with C extensions drastically. Later this year PyPy is expected to reach Python 3.5 conformance.
All this great work inspired me to innovate in one of the areas which Python is used extensively, web and micro-services development.